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N-stride Injection

Knee Service

Colorado Springs Orthopaedic Group

Your knees absorb significant stress with every step, making them particularly vulnerable to injury, overuse, and wear over time. Knee pain can interfere with walking, exercise, work, sports, and many of the activities you enjoy.

CSOG provides comprehensive evaluation and treatment for knee conditions affecting patients of all ages and activity levels. Our specialists treat sports injuries, ligament and meniscus problems, arthritis, fractures, and other conditions using both nonsurgical and surgical approaches.

Depending on your diagnosis, treatment may include physical therapy, medications, injections, bracing, minimally invasive procedures, or surgery. We take your symptoms, activity level, and goals into account when developing your treatment plan, with a focus on reducing pain and helping you regain strength, stability, and function.

What are N-stride Injections?

N-stride injections are used to treat knee osteoarthritis. It is prepared from blood extracted from your body and is rich in anabolic growth factors, special proteins involved in the body’s healing process, and anti-inflammatory proteins responsible for suppressing inflammation in your knee joints.

What is Anatomy of the Knee?

The knee is comprised of three bones – the patella (kneecap), tibia (shinbone) and femur (thighbone) which articulate to form your knee joint. The ends of the bones are covered with a smooth layer of articular cartilage that prevents friction between the knee bones and facilitates smooth movements by helping them to glide over each other.

What is Knee Arthritis?

Knee arthritis is caused from damage to the articular cartilage of your knees. The damaged cartilage causes friction between the bones in the joint leading to symptoms such as pain, swelling and stiffness in the knees which increases over time.

The most common forms of knee arthritis include osteoarthritis, caused due to degenerative wear and tear of the cartilage and rheumatoid arthritis, an autoimmune disease where the body’s immune cells attack the healthy cartilage.

How Does the N-stride Injection work?

People suffering from knee osteoarthritis have increased levels of proteins such as interleukins, C-reactive proteins and tumor necrosis factor-alpha that attack the cartilage cells in their body. Cartilage injury leads to inflammation and osteoarthritis progression.

The N-stride injection has a high concentration of anti-inflammatory cytokines and anabolic growth factors that help heal the damaged cartilage cells and provide relief from osteoarthritis pain and discomfort. It also prevents further cartilage destruction by reversing the effects of the inflammatory proteins in osteoarthritis affected knee joints.

What is the Procedure for N-stride Injection?

Your surgeon draws a blood sample from your arm, which is then centrifuged or spun to separate the plasma, the liquid component of blood, from the solid components including the platelets, red blood cells (RBCs) and white blood cells (WBCs. The plasma is collected and further processed to obtain a concentrated level of anabolic growth factors and cytokines. The fortified plasma sample is then injected into the knee under ultrasound guidance.

The entire procedure may take around 20 to 30 minutes.

What Happens After N-stride Injection?

  • You may experience pain relief after one week following the N-stride injection. Take prescribed medications to relieve pain and discomfort in the meantime.
  • You should rest your knee for two weeks after which you can resume your regular activities.

What are the Benefits of N-stride Injection?

The N-stride injection is well tolerated and offers the following benefits:

  • It is quick and performed in an outpatient setting
  • Offers long-lasting results up to 12 months after the procedure
  • Suitable for patients who do not want surgery

What are the Risks and Complications of N-stride Injection?

N-stride injection may cause some unwanted effects such as:

  • Discomfort and joint pain at the injection site
  • Nausea

These symptoms will resolve on their own. However, you should call your doctor if your symptoms increase over time.

For more information about our services or to schedule an appointment, call us at or click here to request an appointment online. We'll respond to you as soon as possible.

How Can You Reach CSOG Knee Center
  • Schedule An Appointment
  • Send a Referral
  • Send Medical Records
    Powershare Image Upload
  • Additional Inquires
Knee Center Specialists
Colorado Springs Locations
Orthopaedic Care Across Colorado Springs

Visit CSOG at convenient locations for specialty care, Express Care, imaging, therapy, and recovery support.

North Campus

4110 Briargate Parkway
Suite 300
Colorado Springs, CO 80920

Mon - Thu : 7:00 am to 5:00 pm
Fri : 7:00 am to 4:00 pm

Schedule an Appointment
South Campus

1655 Quail Lake Loop
Colorado Springs, CO 80906

Mon - Thu : 7:00 am to 5:00 pm
Fri : 7:00 am to 4:00 pm

Schedule an Appointment
East Campus

6140 Tutt Blvd
Suite 110
Colorado Springs, CO 80923

Mon - Fri : 7:00 am to 6:00 pm

Schedule an Appointment
Ready to Take the Next Step Toward Better Movement?

Whether you are dealing with a new injury, chronic pain, arthritis, or recovery after surgery, CSOG can help you find the right orthopaedic care path.

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idtitlepage_urlspecialty_idtypeslugstatus
505Knee Arthroscopy/knee/knee-arthroscopy-orthopaedic-specialists-colorado-springs-co/151knee-arthroscopy1
506Knee Ligament Reconstruction/knee/knee-ligament-reconstruction-orthopaedic-specialists-colorado-springs-co/151knee-ligament-reconstruction1
507Minimally Invasive Knee Joint Replacement/knee/minimally-invasive-knee-joint-replacement-orthopaedic-specialists-colorado-springs-co/151minimally-invasive-knee-joint-replacement1
508Knee Preservation Surgery/knee/knee-preservation-surgery-orthopaedic-specialists-colorado-springs-co/151knee-preservation-surgery1
509Knee Surgery/knee/knee-surgery-orthopaedic-specialists-colorado-springs-co/151knee-surgery1
510Knee Fracture Surgery/knee/knee-fracture-surgery-orthopaedic-specialists-colorado-springs-co/151knee-fracture-surgery1
511Knee Osteoarthritis Treatment/knee/knee-osteoarthritis-treatment-orthopaedic-specialists-colorado-springs-co/151knee-osteoarthritis-treatment1
512Visionaire Knee Replacement/knee/visionaire-knee-replacement-orthopaedic-specialists-colorado-springs-co/151visionaire-knee-replacement1
513Primary Knee Replacement/knee/primary-knee-replacement-orthopaedic-specialists-colorado-springs-co/151primary-knee-replacement1
514Total Knee Replacement/knee/total-knee-replacement-orthopaedic-specialists-colorado-springs-co/151total-knee-replacement1
515PCL Reconstruction/knee/pcl-reconstruction-orthopaedic-specialists-colorado-springs-co/151pcl-reconstruction1
516LCL Reconstruction/knee/lcl-reconstruction-orthopaedic-specialists-colorado-springs-co/151lcl-reconstruction1
517ACL Reconstruction/knee/acl-reconstruction-orthopaedic-specialists-colorado-springs-co/151acl-reconstruction1
518Revision Knee Replacement/knee/revision-knee-replacement-orthopaedic-specialists-colorado-springs-co/151revision-knee-replacement1
519Robotic Assisted Knee Replacement/knee/robotic-assisted-knee-replacement-orthopaedic-specialists-colorado-springs-co/151robotic-assisted-knee-replacement1
520Complex Total Knee Replacement/knee/complex-total-knee-replacement-orthopaedic-specialists-colorado-springs-co/151complex-total-knee-replacement1
521Outpatient Total Knee Replacement/knee/outpatient-total-knee-replacement-orthopaedic-specialists-colorado-springs-co/151outpatient-total-knee-replacement1
522Computer Navigation for Total Knee Replacement/knee/computer-navigation-total-knee-replacement-orthopaedic-specialists-colorado-springs-co/151computer-navigation-for-total-knee-replacement1
523Meniscal Repair Surgery/knee/meniscal-repair-surgery-orthopaedic-specialists-colorado-springs-co/151meniscal-repair-surgery1
524Quadriceps Tendon Repair/knee/quadriceps-tendon-repair-orthopaedic-specialists-colorado-springs-co/151quadriceps-tendon-repair1
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SELECT 
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FROM 
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idtitlepage_urlspecialty_idtypeslugstatus
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550ACL Tears/knee/acl-tears-orthopaedic-specialists-colorado-springs-co/152acl-tears1
551Knee Pain/knee/knee-pain-orthopaedic-specialists-colorado-springs-co/152knee-pain1
552Jumper's Knee/knee/jumpers-knee-orthopaedic-specialists-colorado-springs-co/152jumper-s-knee1
553Patellar Instability/knee/patellar-instability-orthopaedic-specialists-colorado-springs-co/152patellar-instability1
554Osteochondritis Dissecans of the Knee/knee/osteochondritis-dissecans-knee-orthopaedic-specialists-colorado-springs-co/152osteochondritis-dissecans-of-the-knee1
555MCL Tears/knee/mcl-tears-orthopaedic-specialists-colorado-springs-co/152mcl-tears1
556Knee Injury/knee/knee-injury-orthopaedic-specialists-colorado-springs-co/152knee-injury1
557Knee Sprain/knee/knee-sprain-orthopaedic-specialists-colorado-springs-co/152knee-sprain1
558Meniscal Injuries/knee/meniscal-injuries-orthopaedic-specialists-colorado-springs-co/152meniscal-injuries1
559Meniscal Tears/knee/meniscal-tears-orthopaedic-specialists-colorado-springs-co/152meniscal-tears1
560Knee Ligament Injuries/knee/knee-ligament-injuries-orthopaedic-specialists-colorado-springs-co/152knee-ligament-injuries1
561Multiligament Instability/knee/multiligament-instability-orthopaedic-specialists-colorado-springs-co/152multiligament-instability1
562Patellar Dislocation/Patellofemoral Dislocation/knee/patellar-dislocation-patellofemoral-dislocation-orthopaedic-specialists-colorado-springs-co/152patellar-dislocation-patellofemoral-dislocation1
563PCL Injuries/knee/pcl-injuries-orthopaedic-specialists-colorado-springs-co/152pcl-injuries1
564Patellofemoral Instability/knee/patellofemoral-instability-orthopaedic-specialists-colorado-springs-co/152patellofemoral-instability1
565Patella Fracture/knee/patella-fracture-orthopaedic-specialists-colorado-springs-co/152patella-fracture1
566Quadriceps Tendon Rupture/knee/quadriceps-tendon-rupture-orthopaedic-specialists-colorado-springs-co/152quadriceps-tendon-rupture1
567Patellofemoral Arthritis/knee/patellofemoral-arthritis-orthopaedic-specialists-colorado-springs-co/152patellofemoral-arthritis1
568Posterolateral Instability/knee/posterolateral-instability-orthopaedic-specialists-colorado-springs-co/152posterolateral-instability1
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